Full Name: β- Nicotiamide mononucleotide
CAS No.: 1094-61-7
Formula weight: 334.22
Formula: C11H15N2O8P
Purity: >95% (HPLC)
Water contents: <8%
Spectral analysis
1. εat 260nm and pH7.5 (4.2 ±0.2) x 10 3 L・mole -1・cm-1
2. Ratio at pH7.5 A265/A260 1.08 ±0.03
A290/A260 0.21 ± 0.02
Metal Contents
1. Mg <= 0.001%
2. Ni: <= 0.001%
Condition for Storage: Store below -20 ℃
Remark: The product is for research use only, not for medical use.
Reference:
1) Yoshino J, Mills KF, Yoon MJ, Imai S (2011) Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 14 : 528-536
2) Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA.(2013) Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell 155 : 1624-1638
3) Yamamoto T, Byun J, Zhai P, Ikeda Y, Oka S, Sadoshima J. (2014) Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, Protects the heart from ischemia and reperfusion. PLoS One. 9 : e98972
4) Stein LR, Imai S (2014) Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging. EMBO J. 33: 1321-1340